54gene to advance genomics research in Africa, awards $64,000 scholarship to 4 Africans

54gene has awarded scholarships to four African PhD candidates to advance genomics research on the continent.

The healthtech startup advancing African genomics research for improved global health outcomes has awarded $64,000 scholarships to four PhD candidates in Nigeria, Uganda and South Africa to bridge the divide in the global genomics market.

The four recipients include: Rejoice Gomera - University of Pretoria, South Africa; Christopher Kintu - Makerere University, Uganda; Abimbola Onyia - Covenant University, Nigeria and Chisom Soremekun - Makerere University, Uganda.

The $64,000 will cover all expenses of the recipients during their postgraduate study, the scholarship is a project led by the African Centre for Translational Genetics (ACTG), a non-profit initiative launched by 54gene in February 2020.

In 2021, the PhD scholarship awards were the primary focus for the ACTG as part of the Centre's broad vision to invest in the continent’s health ecosystem by empowering the next generation of African genomics scientists through the provision of scholarships, grants, fellowships, internships and training programmes.

Following a three month pan-African call for applications and a rigorous selection process, four successful recipients were handpicked from a total of 46 applications and were awarded grants to advance their genomics research studies in the areas of cardiometabolic diseases, cancers, neurological diseases and sickle cell disorders.

According to Dr. Abasi Ene-Obong, CEO of 54gene: "Developing the next generation of genomic scientists is critical in ensuring that the knowledge, resources and insights derived from homegrown research benefits not only Africans but the global population."

Dr Ene-Obong added that "access to funding as well as to our international team of genetic and bio-medical specialists is a unique opportunity for these talented African researchers who, like us, want to unlock the boundless potential offered by the human genomic diversity of African populations. The funding and available resources will put them at par with their counterparts in developed countries and make them more confident in leading future research studies".

Less than 3% of genetic material used in global pharmaceutical research is from Africa. The staggering gap is quite surprising because Africans and people of African descent are reported to be more genetically diverse than any other population.

"There is incredible African talent in the genomics space, but opportunities to undertake research and conduct desired tests is limited due to inadequate infrastructure", Aminu Yakubu, VP Research Governance and Ethics at 54gene and ACTG representative stated.

Adding that "Supporting and powering pan-African genomics research, especially for non-communicable diseases, has been a key impact marker for 54gene since the company launched in 2019.

This is why we are thrilled to offer these outstanding researchers the opportunity to carry out ground-breaking research that will contribute to future health outcomes and benefit the field of genomics research on the continent and also globally."

With over $45 million in investment raised by the company since its launch, the PhD candidates will receive up to $4,000 annually for four years, to cover tuition fees and living expenses.

54gene, through the ACTG in 2020, launched the NCD-GHS Consortium composed of Nigerian geneticists in partnership with the Nigerian Institute of Medical Research (NIMR) and the National Biotechnology Development Agency’s Center for Genomics Research and Innovation (NABDA-CGRI).

Recipients will have the opportunity to work alongside leading researchers at 54gene and its partner institutions (NIMR and CGRI), who are experts in genomic data science, bioinformatics and molecular genetics. Recipients will also be given access to state-of-the-art genomic technologies and the opportunity to co-publish novel findings in collaboration with these leading scientists.

Preliminary findings from the Consortium’s landmark study into non-communicable and cardio-metabolic diseases were shared at the American Society of Human Genetics Conference in October, 2021.

The study found seven distinct clusters among the 50 under-studied ethnolinguistic groups in Nigeria with some groups showing evidence of shared genomic regions with northern African and European groups. In comparison to European populations, the study also replicated previous research showing lower levels of Neanderthal genome sharing in Nigerian groups.

As 54gene expands its operations and partnerships in the coming years, the ACTG looks forward to equally expanding the coverage of its empowerment activities to reach more research scientists in academia and research institutes.

Through these efforts, the ACTG is building on the giant precedent work undertaken by organizations like the Human Hereditary and Health in Africa (H3Africa) Consortium, and the African Academy of Sciences among others.